Peptide Database

Peptide NameHepcidin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length96 amino acids

Chemical FormulaC440H703N123O135S11

DescriptionStandard

        MKVFSIAAAVTLVLAFVSLLESSALPLDQVQETEGVGMVRGAGMSDTPAAANEETSVDQWITPYHARVKRGGLVALCRYCCNCCRSNSGCGFCCKY
    

Molecular Weight10228.75 Da

Isoelectric Point (pI)6.52

Net Charge (pH 7.0)-0.48

Net Charge (pH 7.4) -0.88

Charge Density (pH 7.0) -0.0050

GRAVY Index0.27

Hydrophobic Moment 0.65

Boman Index0.12

Instability Index29.84

Aliphatic Index 82.29

Aromaticity 0.0729

Extinction Coeff. Reduced 9970.00

Extinction Coeff. Oxidized 10470.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4114.10

LogP -46.06

H-bond Donors 152.0

H-bond Acceptors 147.0

Rotatable Bonds 332.0

Heavy Atoms 709.0

Ring Count 12.0

Amide Bonds 101.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0200439 VERIFIED: NO

Provenance & Taxonomy

OrganismCynoglossus semilaevis [Animal]

FamilyHepcidin

Tax ID244447

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Non-hemolytic Non-ribosomal

RECORD: Rec_0275067 VERIFIED: NO