Peptide Database

Peptide NameMelittin [G1I]

Function Ontology

Anticancer

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Antimicrobial ▸ Antibacterial

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length26 amino acids

Chemical FormulaC135H236N38O32

DescriptionStandard

        IIGAVLKVLTTGLPALISWIKRKRQQ
    

Molecular Weight2903.55 Da

Isoelectric Point (pI)12.00

Net Charge (pH 7.0)4.76

Net Charge (pH 7.4) 4.55

Charge Density (pH 7.0) 0.1830

GRAVY Index0.46

Hydrophobic Moment 0.57

Boman Index0.14

Instability Index48.00

Aliphatic Index 150.00

Aromaticity 0.0385

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1146.55

LogP -7.07

H-bond Donors 41.0

H-bond Acceptors 37.0

Rotatable Bonds 99.0

Heavy Atoms 205.0

Ring Count 3.0

Amide Bonds 27.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0425621 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyMelittin

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

TargetListeria monocytogenes F4244

Activity5.3658

MethodMBC

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