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MYP_049472
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Basic Information
Peptide 25
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
not Standard
13 amino acids
-
contains X representing unresolved or non-standard residue
Sequence
FVPWFXKFLXRIL
Physicochemical Analysis
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Residue Composition
Amino Acid Composition
Chemical Descriptors
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0075653 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Defensin
32630
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
(S)-2-(4-pentenyl)alanine at 6,10; propargylalanine, Z = azidolysine; (S)-2-(4-pentenyl)alanine
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcus epidermidis ATCC 12228
100 μM
MIC
PMID34296619 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/34296619/
RECORD: Rec_0078629 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Defensin
32630
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
propargylalanine, Z = azidolysine at 6; non-canonical residue code at 10; propargylalanine, Z = azidolysine
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus ATCC 25923
3.12 μM
MIC
PMID34296619 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/34296619/
RECORD: Rec_0113573 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Defensin
32630
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
propargylalanine, Z = azidolysine at 6; non-canonical residue code at 10; propargylalanine, Z = azidolysine
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Pseudomonas aeruginosa ATCC 27853
100 μM
MIC
PMID34296619 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/34296619/
RECORD: Rec_0130743 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Defensin
32630
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
(S)-2-(4-pentenyl)alanine at 6,10; propargylalanine, Z = azidolysine; (S)-2-(4-pentenyl)alanine
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Acinetobacter baumannii ATCC 19606
100 μM
MIC
PMID34296619 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/34296619/
RECORD: Rec_0211481 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Defensin
32630
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
(S)-2-(4-pentenyl)alanine at 6,10; propargylalanine, Z = azidolysine; (S)-2-(4-pentenyl)alanine
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Escherichia coli ATCC 25922
100 μM
MIC
PMID34296619 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/34296619/
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