Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length451 amino acids

Chemical FormulaC2293H3632N622O627S9

DescriptionStandard

        TNPGFVVRITQAGLDYAQEQGIAILEKELAQLKLPDFSGKSGKVRYSFSRLRIPTFRLPHSRITPVPNVGLQVSISNAFAELNGDWRVKFLFIKGHGSFNLKVENVNMKIILRLGSDTTGRPTISTSDCSARASKVGLRFSGKLAWLYNLFHRVIERKLRKNLESKVCDNVAKSVHNELQTYMRTLPVTAKIDNKFGIDYSLVAPPRATAQSLDADLKGEFYSLAHRSPVPFSPLPLAFPSDHERMVYFGASSYFFNTAGIAYHEAGALVFEITEAMIPKEARFTLDTSIFSAFIPQLKEKYPNMPMKFRLSAPTAPFLTIGPGGISFQPIVDIQAYAILPNSKLAPLFLLSLVRNVSAVINVRSGRIVGSLDVGRIRLSLKDSAVGTFQVQFLQSIMNILTSNVLLPHLNARLDEGFPLPLLDRIQLSNILVRFHQNFLLLGADVRFQPR
    

Molecular Weight50233.74 Da

Isoelectric Point (pI)9.95

Net Charge (pH 7.0)19.19

Net Charge (pH 7.4) 18.43

Charge Density (pH 7.0) 0.0426

GRAVY Index0.04

Hydrophobic Moment 0.87

Boman Index0.08

Instability Index34.02

Aliphatic Index 100.98

Aromaticity 0.0976

Extinction Coeff. Reduced 27390.00

Extinction Coeff. Oxidized 27515.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0289772 VERIFIED: NO

Provenance & Taxonomy

OrganismMolothrus ater [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria