Peptide Database

Peptide NameHepcidin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length91 amino acids

Chemical FormulaC453H735N127O123S12

DescriptionStandard

        MKSISVVCAVALTVTCICILQTTAVPFSQSEITEHQIRAPKKKSTYKYKVTNSFALFVQVLFRTKRQSHLSLCRYCCNCCKNKGCGFCCRF
    

Molecular Weight10313.24 Da

Isoelectric Point (pI)9.47

Net Charge (pH 7.0)11.56

Net Charge (pH 7.4) 11.06

Charge Density (pH 7.0) 0.1270

GRAVY Index0.17

Hydrophobic Moment 0.60

Boman Index0.01

Instability Index40.18

Aliphatic Index 78.13

Aromaticity 0.0989

Extinction Coeff. Reduced 4470.00

Extinction Coeff. Oxidized 5095.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4069.47

LogP -42.48

H-bond Donors 156.0

H-bond Acceptors 149.0

Rotatable Bonds 344.0

Heavy Atoms 715.0

Ring Count 13.0

Amide Bonds 98.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0089569 VERIFIED: NO

Provenance & Taxonomy

OrganismAstyanax mexicanus [Animal]

FamilyHepcidin

Tax ID7994

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Non-hemolytic Non-ribosomal