‹ ›
MYP_049419
← PREVIOUS NEXT → BACK
Basic Information
Rugosin-LK2
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
33 amino acids
C148H266N42O46S3
Standard
Sequence
SIRDKGKTIAIDLAKSAGTGVLKTLMCKLDKSC
Physicochemical Analysis
3466.14 Da
9.51
3.44
3.19
0.1042
0.03
0.53
-0.03
-1.01
100.61
0.0000
0.00
125.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1445.82
-15.96
54.0
53.0
125.0
239.0
0.0
32.0
Structural Visualization
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
Experimental Records
RECORD: Rec_0190747 VERIFIED: YES
Provenance & Taxonomy
Limnonectes kuhlii [Animal]
Brevinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus ATCC 43300
10 μg/mL
MIC
PMID23054029 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23054029/
RECORD: Rec_0206017 VERIFIED: YES
Provenance & Taxonomy
Limnonectes kuhlii [Animal]
Brevinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Candida albicans ATCC 2002
10 μg/mL
MIC
PMID23054029 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23054029/
RECORD: Rec_0208241 VERIFIED: YES
Provenance & Taxonomy
Limnonectes kuhlii [Animal]
Brevinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Pseudomonas aeruginosa ATCC 27853
2.5 μg/mL
MIC
PMID23054029 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23054029/
RECORD: Rec_0232556 VERIFIED: YES
Provenance & Taxonomy
Limnonectes kuhlii [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
27-33
Bio-Activity Profile
Antimicrobial Antifungal
Bacillus subtilis
30 μg/mL
MIC
PaperFive novel antimicrobial peptides from the Kuhl's wart frog skin secretions, Limnonectes kuhlii.
RECORD: Rec_0284112 VERIFIED: YES
Provenance & Taxonomy
Limnonectes kuhlii [Animal]
Brevinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
FIRST PREV 1 2 3 4 NEXT LAST
Showing 5 records on this page · Page 3 of 4