Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length485 amino acids

Chemical FormulaC2389H3770N612O702S17

DescriptionStandard

        MLSLLILLLNLTNHAFGQNPAIKAILTNKGLQYGSHIGADWMQEKIGSVIIPDVRGGVDIGIGTVHYVLDRISVSGCDVPEPSVEFYEGVGLKAVISGLSISMSGNWHTTFGIITDGGSFDLAVFNVDVTSVVQIGSDLSGHISISSENCDARVGEASINFHGGASLIFQPFVSLFHNRIKAIIEERICPVVEEHVTDLERHLSEMQVSFKVNSALVLDVPLINSPLVDSISLGLNLKGEFYSVQSHTDPPFKAEPFNLPEDKGHMLSLGLSEFTINSASYAYFSAGLLQAQINDSMIPKTSPFRLNTTSFGPLIPQLPKLFPNMLMELQVYARDAPMFSFQADKVTLEFLGAVKAFAIQPNASRTPLFKLNVDSIFSGMIRISEEKVKGLMELSNFTLTLASSEVGTFQTAALENFMKLGMKISVLAKLNAKLEEGIVLPTMHHIHLVNPVLKIQQGFVSIASDLDVKSGERESISEGIYPYRL
    

Molecular Weight52842.27 Da

Isoelectric Point (pI)5.38

Net Charge (pH 7.0)-14.24

Net Charge (pH 7.4) -15.31

Charge Density (pH 7.0) -0.0294

GRAVY Index0.21

Hydrophobic Moment 0.64

Boman Index0.19

Instability Index32.90

Aliphatic Index 105.09

Aromaticity 0.0804

Extinction Coeff. Reduced 24410.00

Extinction Coeff. Oxidized 24535.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0050011 VERIFIED: NO

Provenance & Taxonomy

OrganismSalmo trutta [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria