‹ ›
MYP_049388
← PREVIOUS NEXT → BACK
Basic Information
Thanatin 2, Thanatin [G16del]
Antimicrobial
Antimicrobial ▸ Antibacterial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
20 amino acids
C101H176N34O26S3
Standard
Sequence
GSKKPVPIIYCNRRTKCQRM
Physicochemical Analysis
2378.89 Da
10.47
5.74
5.50
0.2868
-0.93
0.31
-0.40
49.86
53.50
0.0500
1490.00
1615.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1009.27
-10.75
38.0
35.0
80.0
164.0
3.0
21.0
Structural Visualization
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
Experimental Records
RECORD: Rec_0154118 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Thanatin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
11-17
APD analysis reveals that this sequence is similar (95.24%) to Thanatin K=R: 15%, I=C=P: 10%. Chemical modification: C-C disulfide bond
Bio-Activity Profile
Antimicrobial
Pseudomonas aeruginosa
5.2 μM
MIC
PaperRole of amino acid residues within the disulfide loop of thanatin, a potent antibiotic peptide.
RECORD: Rec_0158691 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial
Human erythrocytes
20.8 μM
Hemolysis
Paperhttps://pubmed.ncbi.nlm.nih.gov/12297012/ PMID12297012 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12297012/
RECORD: Rec_0171607 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Thanatin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
11-17
APD analysis reveals that this sequence is similar (95.24%) to Thanatin K=R: 15%, I=C=P: 10%. Chemical modification: C-C disulfide bond
Bio-Activity Profile
Antimicrobial
Escherichia coli HB 101
2.6 μM
MIC
PaperRole of amino acid residues within the disulfide loop of thanatin, a potent antibiotic peptide.
RECORD: Rec_0182344 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Toxic Hemolytic
PaperYADAMP: yet another database of antimicrobial peptides PMID22325123 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22325123/
RECORD: Rec_0207203 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Brevinin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Bacillus subtilis
5.2 μM
MIC
PMID12297012 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12297012/
FIRST PREV 1 2 3 NEXT LAST
Showing 5 records on this page · Page 2 of 3