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MYP_049388
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Basic Information
Thanatin 2, Thanatin [G16del]
Antimicrobial
Antimicrobial ▸ Antibacterial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
20 amino acids
C101H176N34O26S3
Standard
Sequence
GSKKPVPIIYCNRRTKCQRM
Physicochemical Analysis
2378.89 Da
10.47
5.74
5.50
0.2868
-0.93
0.31
-0.40
49.86
53.50
0.0500
1490.00
1615.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1009.27
-10.75
38.0
35.0
80.0
164.0
3.0
21.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0061223 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Brevinin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
human red blood cells
0 % hemolysis at 200 μg/mL
Hemolysis
PMID12297012 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12297012/
RECORD: Rec_0074320 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Brevinin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Staphylococcus aureus
20.8 μM
MIC
PMID12297012 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12297012/
RECORD: Rec_0078413 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Thanatin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
11-17
APD analysis reveals that this sequence is similar (95.24%) to Thanatin K=R: 15%, I=C=P: 10%. Chemical modification: C-C disulfide bond
Bio-Activity Profile
Antimicrobial
Staphylococcus aureus
20.8 μM
MIC
PaperRole of amino acid residues within the disulfide loop of thanatin, a potent antibiotic peptide.
RECORD: Rec_0089296 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Brevinin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Salmonella typhimurium
1.3 μM
MIC
PMID12297012 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12297012/
RECORD: Rec_0115164 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Brevinin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Escherichia coli HB101
2.6 μM
MIC
PMID12297012 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12297012/
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