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MYP_049374
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Basic Information
Hytramycin I
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Mycobacterium
not Standard
6 amino acids
-
contains X representing unresolved or non-standard residue
Sequence
AXLIXX
Physicochemical Analysis
0.00 Da
0.00
0.00
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0.00
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Residue Composition
Amino Acid Composition
Chemical Descriptors
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0141753 VERIFIED: YES
Provenance & Taxonomy
Streptomyces hygroscopicus [Bacterium]
Nonribosomal peptide
Structure & Mods
cyclic peptide [Cyclic]
mixed L/D amino-acid peptide [Mixed]
None
None
METH-ALA= Methylated alanine, D-Pip = piperazic acid moieties, D-Allo-ILE= D form of Allo-isoleucine
Bio-Activity Profile
Antimicrobial Antimycobacterial Antibacterial
Mycobacterium tuberculosis resistant to isoniazid (rINH, ATCC 35822)
4.7 μg/mL
MIC
PMID24224794 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24224794/
RECORD: Rec_0143179 VERIFIED: YES
Provenance & Taxonomy
Streptomyces hygroscopicus [Bacterium]
Nonribosomal peptide
Structure & Mods
cyclic peptide [Cyclic]
mixed L/D amino-acid peptide [Mixed]
None
None
METH-ALA= Methylated alanine, D-Pip = piperazic acid moieties, D-Allo-ILE= D form of Allo-isoleucine
Bio-Activity Profile
Antimicrobial Antimycobacterial Antibacterial
Clinical isolate, X004439
4.4 μg/mL
MIC
PMID24224794 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24224794/
RECORD: Rec_0187888 VERIFIED: YES
Provenance & Taxonomy
Streptomyces hygroscopicus [Bacterium]
Nonribosomal peptide
Structure & Mods
cyclic peptide [Cyclic]
mixed L/D amino-acid peptide [Mixed]
None
None
METH-ALA= Methylated alanine, D-Pip = piperazic acid moieties, D-Allo-ILE= D form of Allo-isoleucine
Bio-Activity Profile
Antimicrobial Antimycobacterial Antibacterial
Mycobacterium tuberculosis resistant to streptomycin (rSM, ATCC 35820)
4.7 μg/mL
MIC
PMID24224794 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24224794/
RECORD: Rec_0193359 VERIFIED: YES
Provenance & Taxonomy
Streptomyces hygroscopicus [Bacterium]
Nonribosomal peptide
Structure & Mods
cyclic peptide [Cyclic]
mixed L/D amino-acid peptide [Mixed]
None
None
METH-ALA= Methylated alanine, D-Pip = piperazic acid moieties, D-Allo-ILE= D form of Allo-isoleucine
Bio-Activity Profile
Antimicrobial Antimycobacterial Antibacterial
Mycobacterium tuberculosis H37Rv
6.0 μg/mL
MIC
PMID24224794 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24224794/
RECORD: Rec_0203493 VERIFIED: YES
Provenance & Taxonomy
Streptomyces hygroscopicus [Bacterium]
Nonribosomal peptide
Structure & Mods
cyclic peptide [Cyclic]
mixed L/D amino-acid peptide [Mixed]
None
None
METH-ALA= Methylated alanine, D-Pip = piperazic acid moieties, D-Allo-ILE= D form of Allo-isoleucine
Bio-Activity Profile
Antimicrobial Antimycobacterial Antibacterial
Clinical isolate, X004244
4.7 μg/mL
MIC
PMID24224794 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24224794/
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