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MYP_049374
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Basic Information
Hytramycin I
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Mycobacterium
not Standard
6 amino acids
-
contains X representing unresolved or non-standard residue
Sequence
AXLIXX
Physicochemical Analysis
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Residue Composition
Amino Acid Composition
Chemical Descriptors
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0011530 VERIFIED: YES
Provenance & Taxonomy
Streptomyces hygroscopicus [Bacterium]
Nonribosomal peptide
Structure & Mods
cyclic peptide [Cyclic]
mixed L/D amino-acid peptide [Mixed]
None
None
METH-ALA= Methylated alanine, D-Pip = piperazic acid moieties, D-Allo-ILE= D form of Allo-isoleucine
Bio-Activity Profile
Antimicrobial Antimycobacterial Antibacterial
Clinical isolate, X001354
4.7 μg/mL
MIC
PMID24224794 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24224794/
RECORD: Rec_0026551 VERIFIED: YES
Provenance & Taxonomy
Streptomyces hygroscopicus [Bacterium]
Nonribosomal peptide
Structure & Mods
cyclic peptide [Cyclic]
mixed L/D amino-acid peptide [Mixed]
None
None
METH-ALA= Methylated alanine, D-Pip = piperazic acid moieties, D-Allo-ILE= D form of Allo-isoleucine
Bio-Activity Profile
Antimicrobial Antimycobacterial Antibacterial
Mycobacterium tuberculosis resistant to kanamycin (rKM, ATCC 35827)
4.9 μg/mL
MIC
PMID24224794 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24224794/
RECORD: Rec_0058668 VERIFIED: YES
Provenance & Taxonomy
Streptomyces hygroscopicus [Bacterium]
Nonribosomal peptide
Structure & Mods
cyclic peptide [Cyclic]
mixed L/D amino-acid peptide [Mixed]
None
None
METH-ALA= Methylated alanine, D-Pip = piperazic acid moieties, D-Allo-ILE= D form of Allo-isoleucine
Bio-Activity Profile
Antimicrobial Antimycobacterial Antibacterial
Mycobacterium tuberculosis resistant to capreomycin (rCAP)
4.8 μg/mL
MIC
PMID24224794 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24224794/
RECORD: Rec_0086530 VERIFIED: YES
Provenance & Taxonomy
Streptomyces hygroscopicus [Bacterium]
Nonribosomal peptide
Structure & Mods
cyclic peptide [Cyclic]
mixed L/D amino-acid peptide [Mixed]
None
None
METH-ALA= Methylated alanine, D-Pip = piperazic acid moieties, D-Allo-ILE= D form of Allo-isoleucine
Bio-Activity Profile
Antimicrobial Antimycobacterial Antibacterial
Mycobacterium tuberculosis resistant to moxifloxacin (rMOX)
4.0 μg/mL
MIC
PMID24224794 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24224794/
RECORD: Rec_0120918 VERIFIED: YES
Provenance & Taxonomy
Streptomyces hygroscopicus [Bacterium]
Nonribosomal peptide
Structure & Mods
cyclic peptide [Cyclic]
mixed L/D amino-acid peptide [Mixed]
None
None
METH-ALA= Methylated alanine, D-Pip = piperazic acid moieties, D-Allo-ILE= D form of Allo-isoleucine
Bio-Activity Profile
Antimicrobial Antimycobacterial Antibacterial
Clinical isolate, X003899
4.8 μg/mL
MIC
PMID24224794 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24224794/
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