Peptide Database

Peptide NamePeptide 142

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Standard StatusStandard

Sequence Length19 amino acids

Chemical FormulaC97H165N35O24

DescriptionStandard

        RPDKPRPLSPSPRPPRPVR
    

Molecular Weight2205.57 Da

Isoelectric Point (pI)12.00

Net Charge (pH 7.0)4.76

Net Charge (pH 7.4) 4.56

Charge Density (pH 7.0) 0.2505

GRAVY Index-1.91

Hydrophobic Moment 0.65

Boman Index-0.65

Instability Index102.37

Aliphatic Index 35.79

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 930.08

LogP -10.22

H-bond Donors 31.0

H-bond Acceptors 29.0

Rotatable Bonds 60.0

Heavy Atoms 156.0

Ring Count 8.0

Amide Bonds 18.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0055841 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyDefensin

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-Term1-Amino cyclohexyl carboxylic acid

C-TermAmidation

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-negative

TargetEscherichia coli BW25113

Activity128 μg/mL

MethodMIC