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MYP_049353
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Basic Information
Big gastrin
Gastrointestinal bioactivity
Hormonal / Endocrine ▸ Hormone peptide
Neurological / Signaling ▸ Neuromuscular and muscle activity ▸ Myotropic activity
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide
Regulatory peptide ▸ Biological modulation
Regulatory peptide ▸ Cell-cell communication
Standard
34 amino acids
C176H257N43O54S2
Standard
Sequence
QLGLQDPPHMVADLSKKQGPWVEEEEAAYGWMDF
Physicochemical Analysis
3903.31 Da
4.19
-5.14
-5.41
-0.1512
-0.71
0.45
0.05
66.38
60.29
0.1176
12490.00
12490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1540.38
-10.64
49.0
52.0
124.0
275.0
10.0
36.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0043263 VERIFIED: YES
Provenance & Taxonomy
Ovis aries [Animal]
Gastrin/cholecystokinin
9940
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Pyroglutamate
Amidation
Gln18 Pyroglutamylation; Tyr29 Sulfotyrosine
Bio-Activity Profile
Hormone Gastrointestinal Neuropeptide
PMID5665711 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/5665711/
RECORD: Rec_0158348 VERIFIED: NO
Provenance & Taxonomy
Bos taurus [Animal]
Big gastrin
9913
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
Pyroglutamate
Amidation
18:Pyrrolidone carboxylic acid; 29:Sulfotyrosine
Bio-Activity Profile
Hormone Endocrine Myotropic Receptor modulation
Mammalian: 0.8 hour; Yeast: 10 min; E. coli: >10 hour
RECORD: Rec_0221698 VERIFIED: YES
Provenance & Taxonomy
Capra hircus [Animal]
Big gastrin
9925
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
Pyroglutamate
Amidation
18:Pyrrolidone carboxylic acid; 29:Sulfotyrosine
Bio-Activity Profile
Hormone Endocrine Myotropic
Mammalian: 0.8 hour; Yeast: 10 min; E. coli: >10 hour
PaperSource-linked PubMed record(s) for Big gastrin (Capra hircus): PMID 3763441 PMID3763441 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/3763441/
RECORD: Rec_0255855 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
Gastrin/cholecystokinin
9913
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Pyroglutamate
Amidation
Gln18 Pyroglutamylation; Tyr29 Sulfotyrosine
Bio-Activity Profile
Hormone Gastrointestinal Neuropeptide
PMID5665711 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/5665711/
RECORD: Rec_0282906 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Neuropeptide
Paper数据库级溯源文献：Wang Y, Wang M, Yin S, et al. NeuroPep: a comprehensive resource of neuropeptides. Database (Oxford). 2015:bav038. PMID 25931458; Bin Y, Zhang W, Tang W, et al. Prediction of Neuropeptides from Sequence Information Using Ensemble Classifier and Hybrid Features. J Proteome Res. 2020;19(9):3732-3740. PMID 32786686. PMID25931458;32786686 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25931458/
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