Peptide Database

Peptide NameSLAY-screened peptide P215

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length21 amino acids

Chemical FormulaC94H141N29O37S

DescriptionStandard

        SSNRHLGGSCQSPESDNYSIY
    

Molecular Weight2301.36 Da

Isoelectric Point (pI)5.30

Net Charge (pH 7.0)-1.46

Net Charge (pH 7.4) -1.74

Charge Density (pH 7.0) -0.0696

GRAVY Index-1.15

Hydrophobic Moment 0.36

Boman Index-0.18

Instability Index104.97

Aliphatic Index 37.14

Aromaticity 0.0952

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 2980.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1092.82

LogP -17.68

H-bond Donors 39.0

H-bond Acceptors 38.0

Rotatable Bonds 73.0

Heavy Atoms 161.0

Ring Count 4.0

Amide Bonds 23.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0285856 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

Targetrecombinant Escherichia coli surface-display screening

MethodSLAY screening

PaperAshley T Tucker, Sean P Leonard, Cory D DuBois, Gregory A Knauf, Ashley L Cunningham, Claus O Wilke, M Stephen Trent, Bryan W Davies. Discovery of Next-Generation Antimicrobials through Bacterial Self-Screening of Surface-Displayed Peptide Libraries. Cell. 2018 Jan 25;172(3):618-628.e13. Epub 2018 Jan 4. PMID29307492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29307492/