Peptide Database

Peptide NameLEAP-2

Function Ontology

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Standard StatusStandard

Sequence Length30 amino acids

Chemical FormulaC146H241N47O42S4

DescriptionStandard

        MTPFWRGVSLRPIGASCRDDSECITRLCRK
    

Molecular Weight3455.03 Da

Isoelectric Point (pI)9.21

Net Charge (pH 7.0)2.47

Net Charge (pH 7.4) 2.21

Charge Density (pH 7.0) 0.0825

GRAVY Index-0.36

Hydrophobic Moment 0.64

Boman Index-0.20

Instability Index60.66

Aliphatic Index 65.00

Aromaticity 0.0667

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5625.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1454.00

LogP -15.90

H-bond Donors 57.0

H-bond Acceptors 49.0

Rotatable Bonds 112.0

Heavy Atoms 239.0

Ring Count 5.0

Amide Bonds 29.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0010876 VERIFIED: YES

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

-

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)