Peptide Database

Peptide NameKiller protein of pyocin s3

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Enzyme / Catalytic activity ▸ Hydrolase

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length562 amino acids

Chemical FormulaC2769H4282N778O835S21

DescriptionStandard

        MAIGYYLLVGDKTTCGGQIITGDHTMTFNGRATAREGDKVTCGKHPGTYVIVGGISDMFDMGQRLAGTLDSVSTCPCRARFINSVMDSYEKQEQPRQQAVTPAYTATQNFSSPMKEATTVQSNPPPVTQVPPPPIPVFAKSRQRGKGCTDAGTEAEPANNFGRMGIYQVLSSPTPVTESKPEQPPQGKKHPPEPDKPQDKKLPWYKRWFSDSKGKAEAAATVVAATTRSAVADGETLVMRYIGGGTSSAGRWLAVPNPLTVGLMGLFYSSGLNEGEEDYLNEYHLSEIASQYGKAPTRVRFRWIRDEESGRMTVQGYHVSPESGLDKVPVHMMKLNPATGNYEFWEPGEHRPTILWTPNEQEFKVPPHTGNEEQPFIPSQITVLPIPDKVGSNIESLPMPEEKDFRDYILVFPAGSGMKPVYVMFNTPRNQPGVVTGQGQRVEGNWLNLAGQDMGAPIPSQIADKLRGRRFNNFDDFRRAFWKEVGNDPELSQQFNSHNKEFLKKSYSPYSPRQEHIGNREKYEIHHVKFIKDGGEVYNLDNLRVTTPKRHIEIHSSKGGIK
    

Molecular Weight62503.70 Da

Isoelectric Point (pI)8.09

Net Charge (pH 7.0)2.75

Net Charge (pH 7.4) 1.59

Charge Density (pH 7.0) 0.0049

GRAVY Index-0.68

Hydrophobic Moment 0.68

Boman Index-0.06

Instability Index49.13

Aliphatic Index 60.69

Aromaticity 0.0890

Extinction Coeff. Reduced 73800.00

Extinction Coeff. Oxidized 74050.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0407408 VERIFIED: YES

Provenance & Taxonomy

OrganismPhotorhabdus bodei [Bacterium]

FamilyPyocin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative Antibiotic Bacteriocin Hydrolase Non-hemolytic Non-ribosomal

TargetEscherichia coli (Gram-negative)

PaperWhole-genome-based revisit of Photorhabdus phylogeny: proposal for the elevation of most Photorhabdus subspecies to the species level and description of one novel species Photorhabdus bodei sp. nov., and one novel subspecies Photorhabdus laumondii subsp. clarkei subsp. nov. PMID29877789 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29877789/