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MYP_049139
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Basic Information
Mutacin, or Mutacin B-Ny266
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antibiotic activity
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Standard
22 amino acids
C107H150N26O31S4
Standard
Sequence
FKSWSFCTPGCAKTGSFNSYCC
Physicochemical Analysis
2424.75 Da
8.52
1.72
1.45
0.0781
-0.01
0.17
0.13
13.67
4.55
0.2273
6990.00
7240.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
918.16
-11.65
37.0
37.0
72.0
168.0
7.0
22.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0095754 VERIFIED: YES
Provenance & Taxonomy
Streptococcus mutans [Bacterium]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Listeria spp., Staphylococcus spp., Streptococcus spp., Bacillus spp., Clostridium spp., A. viscosus, Peptostreptococcus spp., C. diphtheriae
0.4-1.6
MIC
PaperPurification and structure of mutacin B-Ny266: a new lantibiotic produced by Streptococcus mutans
RECORD: Rec_0127845 VERIFIED: YES
Provenance & Taxonomy
Streptococcus mutans [Bacterium]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
B. bronchiseptica
49.2 μg/mL
MIC
PaperPurification and structure of mutacin B-Ny266: a new lantibiotic produced by Streptococcus mutans
RECORD: Rec_0149786 VERIFIED: YES
Provenance & Taxonomy
Streptococcus mutans [Bacterium]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
G. vaginalis
0.03
MIC
PaperPurification and structure of mutacin B-Ny266: a new lantibiotic produced by Streptococcus mutans
RECORD: Rec_0164939 VERIFIED: NO
Provenance & Taxonomy
Streptococcus mutans [Bacterium]; Bacteria [Bacterium]
2; 2
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
RECORD: Rec_0204439 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Anticancer
PaperAntiCP 2.0: an updated model for predicting anticancer peptides (benchmark provenance; exact sequence-level experiment paper unresolved here) | https://pubmed.ncbi.nlm.nih.gov/32770192/
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