Peptide Database

Peptide NameGastrin

Function Ontology

Gastrointestinal bioactivity

Hormonal / Endocrine ▸ Hormone peptide

Neurological / Signaling ▸ Neuromuscular and muscle activity ▸ Myotropic activity

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Regulatory peptide ▸ Biological modulation

Standard StatusStandard

Sequence Length17 amino acids

Chemical FormulaC94H122N20O30S2

DescriptionStandard

        QGPWMEEEEAAYGWMDF
    

Molecular Weight2076.22 Da

Isoelectric Point (pI)4.05

Net Charge (pH 7.0)-5.23

Net Charge (pH 7.4) -5.44

Charge Density (pH 7.0) -0.3076

GRAVY Index-0.96

Hydrophobic Moment 0.27

Boman Index0.12

Instability Index90.94

Aliphatic Index 11.76

Aromaticity 0.2353

Extinction Coeff. Reduced 12490.00

Extinction Coeff. Oxidized 12490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 801.53

LogP -3.69

H-bond Donors 26.0

H-bond Acceptors 27.0

Rotatable Bonds 63.0

Heavy Atoms 146.0

Ring Count 7.0

Amide Bonds 17.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0002456 VERIFIED: YES

Provenance & Taxonomy

OrganismCanis familiaris [Animal]

FamilyGastrin/cholecystokinin

Tax ID9615

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermPyroglutamate

C-TermAmidation

Other ModsTyr12 Sulfotyrosine

Bio-Activity Profile

Function

Hormone Gastrointestinal Neuropeptide

RECORD: Rec_0235955 VERIFIED: YES

Provenance & Taxonomy

OrganismMacaca mulatta [Animal]

FamilyGastrin

Tax ID9544

Structure & Mods

Configlinear peptide [Linear]

Chiralitynoncanonical stereochemical modification [Modified]

N-TermPyroglutamate

C-TermAmidation

Other Mods12:Sulfotyrosine

Bio-Activity Profile

Function

Hormone Endocrine Myotropic

Half-LifeMammalian: 0.8 hour; Yeast: 10 min; E. coli: >10 hour

RECORD: Rec_0254522 VERIFIED: YES

Provenance & Taxonomy

OrganismCanis lupus familiaris [Animal]

FamilyGastrin

Tax ID9615

Structure & Mods

Configlinear peptide [Linear]

Chiralitynoncanonical stereochemical modification [Modified]

N-TermPyroglutamate

C-TermAmidation

Other Mods12:Sulfotyrosine

Bio-Activity Profile

Function

Hormone Endocrine Myotropic Receptor modulation

Half-LifeMammalian: 0.8 hour; Yeast: 10 min; E. coli: >10 hour