Peptide Database

Peptide NameAnticoagulant peptide

Function Ontology

Hemostasis ▸ Anticoagulant activity

Hemostasis ▸ Antithrombotic activity

Standard StatusStandard

Sequence Length11 amino acids

Chemical FormulaC64H90N12O24

DescriptionStandard

        DFEEIPEEYLQ
    

Molecular Weight1411.47 Da

Isoelectric Point (pI)4.05

Net Charge (pH 7.0)-5.23

Net Charge (pH 7.4) -5.44

Charge Density (pH 7.0) -0.4753

GRAVY Index-1.16

Hydrophobic Moment 0.47

Boman Index-0.06

Instability Index121.84

Aliphatic Index 70.91

Aromaticity 0.1818

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 595.35

LogP -2.76

H-bond Donors 18.0

H-bond Acceptors 19.0

Rotatable Bonds 45.0

Heavy Atoms 100.0

Ring Count 3.0

Amide Bonds 11.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0028725 VERIFIED: NO

Provenance & Taxonomy

OrganismCrassostrea gigas [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Anticoagulant

RECORD: Rec_0407185 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antithrombotic

PaperThurieau C., Simonet S., Paladino J., Prost J. F., Verbeuren T., Fauch¨¨re J. L.. New N alpha-guanidinobenzoyl derivatives of hirudin-54-65 containing stabilized carboxyl or phosphoryl groups on the side chain of phenylalanine-63. J. Med. Chem., 37, 625-629, 1994. Evidence URLhttps://www.ebi.ac.uk/chembl/compound_report_card/CHEMBL412685/