Peptide Database

Peptide NameBeta-toxin Cn5

Function Ontology

Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Host defense activity

Membrane / Ion-channel modulation ▸ Ion channel inhibition

Membrane / Ion-channel modulation ▸ Sodium channel modulation ▸ Sodium channel inhibitor

Venom / Toxin ▸ General toxin ▸ Toxin

Venom / Toxin ▸ Toxin

Standard StatusStandard

Sequence Length66 amino acids

Chemical FormulaC310H472N80O98S8

DescriptionStandard

        KEGYLVNKSTGCKYGCLLLGKNEGCDKECKAKNQGGSYGYCYAFGCWCEGLPESTPTYPLPNKSCS
    

Molecular Weight7144.06 Da

Isoelectric Point (pI)8.15

Net Charge (pH 7.0)1.68

Net Charge (pH 7.4) 1.33

Charge Density (pH 7.0) 0.0255

GRAVY Index-0.63

Hydrophobic Moment 0.36

Boman Index-0.03

Instability Index46.61

Aliphatic Index 42.88

Aromaticity 0.1212

Extinction Coeff. Reduced 14440.00

Extinction Coeff. Oxidized 14940.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2866.08

LogP -32.98

H-bond Donors 105.0

H-bond Acceptors 108.0

Rotatable Bonds 232.0

Heavy Atoms 496.0

Ring Count 13.0

Amide Bonds 70.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0390607 VERIFIED: YES

Provenance & Taxonomy

OrganismCentruroides noxius [Animal]

FamilySodium channel inhibitor family

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide12-65; 16-41; 25-46; 29-48

Bio-Activity Profile

Function

Toxin Venom Sodium channel inhibitor family Ion channel inhibitor Host defense