Peptide Database

Peptide NameBeta-defensin (Fragment)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length39 amino acids

Chemical FormulaC188H308N60O55S6

DescriptionStandard

        RGKFKEICERPNGSCRDFCLETEIHVGRCLNSRPCCLPL
    

Molecular Weight4481.22 Da

Isoelectric Point (pI)8.34

Net Charge (pH 7.0)1.80

Net Charge (pH 7.4) 1.45

Charge Density (pH 7.0) 0.0461

GRAVY Index-0.44

Hydrophobic Moment 0.43

Boman Index-0.20

Instability Index52.55

Aliphatic Index 67.44

Aromaticity 0.0513

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 375.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1866.34

LogP -20.18

H-bond Donors 71.0

H-bond Acceptors 64.0

Rotatable Bonds 148.0

Heavy Atoms 309.0

Ring Count 6.0

Amide Bonds 40.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0053543 VERIFIED: NO

Provenance & Taxonomy

OrganismPongo pygmaeus [Animal]

FamilyDefensin

Structure & Mods

ConfigSingle-chain peptide backbone represented as a linear sequence entry [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial

RECORD: Rec_0262999 VERIFIED: NO

Provenance & Taxonomy

OrganismPongo pygmaeus [Animal]

FamilyDefensin

Tax ID9600

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence