Peptide Database

Peptide NameChicken Heterophil Peptide 2

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antifungal

Standard StatusStandard

Sequence Length33 amino acids

Chemical FormulaC167H259N45O42S5

DescriptionStandard

        GRKSDCFRKNGFCAFLKCPYLTLISGLCSFHLC
    

Molecular Weight3729.44 Da

Isoelectric Point (pI)9.04

Net Charge (pH 7.0)3.79

Net Charge (pH 7.4) 3.46

Charge Density (pH 7.0) 0.1150

GRAVY Index0.33

Hydrophobic Moment 0.42

Boman Index0.09

Instability Index8.41

Aliphatic Index 73.94

Aromaticity 0.1515

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1740.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1397.81

LogP -12.24

H-bond Donors 55.0

H-bond Acceptors 52.0

Rotatable Bonds 121.0

Heavy Atoms 259.0

Ring Count 7.0

Amide Bonds 33.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0380198 VERIFIED: YES

Provenance & Taxonomy

OrganismGallus gallus [Animal]

FamilyDefensin

Tax ID9031

Structure & Mods

Configlinear peptide [Linear]

Chiralitynoncanonical stereochemical modification [Modified]

Other Modsthree disulfide bonds

Bio-Activity Profile

Function

Antimicrobial Antifungal

TargetB. avium

Activity16 μg/mL

MethodMIC

RECORD: Rec_0399030 VERIFIED: YES