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MYP_048880
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Basic Information
Chicken Heterophil Peptide 2
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Standard
33 amino acids
C167H259N45O42S5
Standard
Sequence
GRKSDCFRKNGFCAFLKCPYLTLISGLCSFHLC
Physicochemical Analysis
3729.44 Da
9.04
3.79
3.46
0.1150
0.33
0.42
0.09
8.41
73.94
0.1515
1490.00
1740.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1397.81
-12.24
55.0
52.0
121.0
259.0
7.0
33.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0200944 VERIFIED: YES
Provenance & Taxonomy
Gallus gallus [Animal]
Defensin
9031
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
three disulfide bonds
Bio-Activity Profile
Antimicrobial Antifungal
M. gallisepticum
16 μg/mL
MIC
PaperIsolation of antimicrobial peptides from avian heterophils.
RECORD: Rec_0279231 VERIFIED: YES
Provenance & Taxonomy
Gallus gallus [Animal]
Defensin
9031
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
PMID7964174 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/7964174/
RECORD: Rec_0296990 VERIFIED: YES
Provenance & Taxonomy
Gallus gallus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
RECORD: Rec_0340160 VERIFIED: YES
Provenance & Taxonomy
Gallus gallus [Animal]
Defensin
9031
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
three disulfide bonds
Bio-Activity Profile
Antimicrobial Antifungal
S. enteriditis
8 μg/mL
MIC
PaperIsolation of antimicrobial peptides from avian heterophils.
RECORD: Rec_0360006 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antibacterial Antimicrobial Antifungal Anti-Gram-positive Anti-Gram-negative
PaperYADAMP: yet another database of antimicrobial peptides PMID22325123 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22325123/
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