Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length415 amino acids

Chemical FormulaC2065H3266N552O584S15

DescriptionStandard

        TNPGVVVRITQAGLDYAHQQGIMILEKELAQLKLPDISGDTRVLRVGKVRYELSRLRLREFHLPYSRITPVSNVGLQVSIANAFAELDGDWRVKLFFVSVPSSSSSYSGIHSVSPTLDPDRFFSSLSLLCFGHLQPRNGTAHMTVEVICSQLSPPCHSSLFLMLTVTARIDSKTGIDYSLVAPPRATAQYLDLDLKGEFYSLAKRSTVPFSPLPLAFPSDHDRMVYFGVSSYFLNTAGIAYQKAGALVFEITEAMVPKEAGFRLDTSVFSAFIPQLEEMYPNMPMKFRLSAPTAPFLTIGPGGISFQPIVDAQAYAILPDASLAPLFLLSLVRNVSAVINERSGRIVGSVNVGRIRLSLKESAVGTFQVRMMQSIMNVITSSTLLPRVNARLNEGWHLPMPNGVQLSNVLVKFHQ
    

Molecular Weight45650.34 Da

Isoelectric Point (pI)9.18

Net Charge (pH 7.0)6.19

Net Charge (pH 7.4) 5.43

Charge Density (pH 7.0) 0.0149

GRAVY Index0.16

Hydrophobic Moment 0.69

Boman Index0.13

Instability Index36.46

Aliphatic Index 99.81

Aromaticity 0.0892

Extinction Coeff. Reduced 28880.00

Extinction Coeff. Oxidized 29005.00

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Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0338164 VERIFIED: NO

Provenance & Taxonomy

OrganismErithacus rubecula [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria