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MYP_048790
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Basic Information
Defensin
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Host defense activity
Standard
40 amino acids
C170H275N57O52S6
Standard
Sequence
ATCDLASGFGVGSSLCAAHCIARRYRGGYCNSKAVCVCRN
Physicochemical Analysis
4141.74 Da
8.94
3.82
3.49
0.0955
0.23
0.52
0.03
23.38
66.00
0.0750
2980.00
3355.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1765.61
-24.87
71.0
63.0
133.0
285.0
4.0
41.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0322927 VERIFIED: YES
Provenance & Taxonomy
Anopheles gambiae [Animal]
Defensin
7165
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Disulfide bond(s) reported
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
dose causing the first signs of toxicity on mice
PaperPubMed PMID: 8799739 | PubMed PMID: 18214975 PMID8799739;18214975 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/8799739/
RECORD: Rec_0387319 VERIFIED: YES
Provenance & Taxonomy
Anopheles gambiae [Animal]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
Staphylococcus aureus strain 4
PMID18214975 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18214975/
RECORD: Rec_0401121 VERIFIED: YES
Provenance & Taxonomy
Anopheles gambiae [Animal]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
Staphylococcus aureus strain 21
PMID18214975 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18214975/
RECORD: Rec_0411810 VERIFIED: YES
Provenance & Taxonomy
Anopheles gambiae [Animal]
Defensin
7165
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Disulfide bond(s) reported
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
Staphylococcus aureus strain 21
6.25 μg/mL
IC90
PaperPubMed PMID: 8799739 | PubMed PMID: 18214975 PMID8799739;18214975 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/8799739/
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