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MYP_048790
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Basic Information
Defensin
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Host defense activity
Standard
40 amino acids
C170H275N57O52S6
Standard
Sequence
ATCDLASGFGVGSSLCAAHCIARRYRGGYCNSKAVCVCRN
Physicochemical Analysis
4141.74 Da
8.94
3.82
3.49
0.0955
0.23
0.52
0.03
23.38
66.00
0.0750
2980.00
3355.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1765.61
-24.87
71.0
63.0
133.0
285.0
4.0
41.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0183174 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
PaperAPD2: the updated antimicrobial peptide database and its application in peptide design PMID18957441 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18957441/
RECORD: Rec_0198417 VERIFIED: YES
Provenance & Taxonomy
Anopheles gambiae [Animal]
invertebrate defensin family
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
3-30; 16-36; 20-38
Bio-Activity Profile
Antimicrobial invertebrate defensin family Antibacterial Host defense Defensin-like
PaperPDB 2E3E structural record; NMR; chain A; residues 1-40
RECORD: Rec_0309238 VERIFIED: YES
Provenance & Taxonomy
Anopheles gambiae [Animal]
Defensin
7165
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Disulfide bond(s) reported
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
PaperPubMed PMID: 8799739 | PubMed PMID: 18214975 PMID8799739;18214975 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/8799739/
RECORD: Rec_0318187 VERIFIED: YES
Provenance & Taxonomy
Anopheles gambiae [Animal]
Defensin
7165
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Disulfide bond(s) reported
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
T2>100 mg/kg
PaperPubMed PMID: 8799739 | PubMed PMID: 18214975 PMID8799739;18214975 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/8799739/
RECORD: Rec_0320828 VERIFIED: YES
Provenance & Taxonomy
Anopheles gambiae [Animal]
Defensin
7165
Structure & Mods
Disulfide-stabilized peptide [Linear]
noncanonical stereochemical modification [Modified]
three disulfide bonds
Bio-Activity Profile
Antimicrobial Antifungal
Fusarium culmorum
3-6 μM
MIC
PaperUse of Defensins to Develop Eco-Friendly Alternatives to Synthetic Fungicides to Control Phytopathogenic Fungi and Their Mycotoxins PMID35330231 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35330231/
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