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MYP_048771
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Basic Information
Unnamed
Cardiovascular ▸ Blood pressure regulation ▸ Antihypertensive
Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory
Enzyme modulation ▸ Enzyme inhibition ▸ Glycosidase inhibition ▸ Alpha-glucosidase inhibitory
Enzyme modulation ▸ Enzyme inhibition ▸ Lipase inhibition
Membrane / Ion-channel modulation ▸ Calcium channel modulation ▸ Calcium channel inhibitor
Metabolic ▸ Glucose metabolism ▸ Antidiabetic
Other / Curated residual function label ▸ Generic enzyme inhibition annotation
Standard
7 amino acids
C27H44N10O12
Standard
Sequence
AGDDAPR
Physicochemical Analysis
700.70 Da
4.21
-1.20
-1.39
-0.1717
-1.41
0.71
-0.36
25.31
28.57
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
365.63
-5.30
12.0
11.0
20.0
49.0
1.0
6.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0019940 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive ACE inhibitory
Angiotensin-converting enzyme (ACE)
11.91
IC50
PaperZieli¨½ska E., Kara? M., Baraniak B., Jakubczyk A.. Evaluation of ACE, alpha?glucosidase, and lipase inhibitory activities of peptides obtained by in vitro digestion of selected species of edible insects. Eur. Food Res. Technol., 246, 1361-1369, 2020.
RECORD: Rec_0205962 VERIFIED: YES
Provenance & Taxonomy
Tenebrio molitor [Animal]
Angiotensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Enzyme inhibitory ACE inhibitory
Angiotensin-converting enzyme
8.34 ± 0.02 μg/mL
IC50
RECORD: Rec_0254714 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Metabolic Syndrome Pancreatic lipase inhibitory
Pancreatic lipase
110.61
IC50
PaperZieli¨½ska E., Kara? M., Baraniak B., Jakubczyk A.. Evaluation of ACE, alpha?glucosidase, and lipase inhibitory activities of peptides obtained by in vitro digestion of selected species of edible insects. Eur. Food Res. Technol., 246, 1361-1369, 2020.
RECORD: Rec_0377979 VERIFIED: YES
Provenance & Taxonomy
Tenebrio molitor [Animal]
Angiotensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Enzyme inhibitory
alpha-glucosidase
19.47 ± 0.2 μM
IC50
RECORD: Rec_0394499 VERIFIED: YES
Provenance & Taxonomy
Tenebrio molitor [Animal]
Angiotensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Enzyme inhibitory
lipase
77.46 ± 0.8 μg/mL
IC50
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