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MYP_048761
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Basic Information
pentapeptide
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Delivery / Targeting ▸ Cell penetration ▸ Cell-penetrating peptide
Delivery / Targeting ▸ Drug delivery vehicle
Delivery / Targeting ▸ Targeting ligand ▸ Targeting
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
5 amino acids
C27H43N9O8
Standard
Sequence
RGDFK
Physicochemical Analysis
621.69 Da
8.75
0.76
0.56
0.1520
-1.90
0.52
-0.65
-54.12
0.00
0.2000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
304.94
-2.92
11.0
9.0
21.0
44.0
1.0
4.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0098204 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Source entry describes small-molecule/peptide conjugation at one terminus; exact terminus not explicitly assigned in source metadata
Conjugate type: amide; Conjugated small molecule: ureidopyrimidinone
Bio-Activity Profile
-
PaperSolid-phase-based synthesis of ureidopyrimidinone-peptide conjugates for supramolecular biomaterials. Synlett. 2015 Evidence URLhttps://doi.org/10.1055/s-0035-1560520
RECORD: Rec_0215831 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Source entry describes small-molecule/peptide conjugation at one terminus; exact terminus not explicitly assigned in source metadata
Conjugate type: sulfonamide; Conjugated small molecule: 3,4-dihydro-2,2,5,7,8-pentamethyl-2H-1-benzopyran-6-sulfonic acid
Bio-Activity Profile
Anticancer Imaging
Paper1-Ethoxyethylidene, a New Group for the Stepwise SPPS of Aminooxyacetic Acid Containing Peptides Evidence URLhttps://doi.org/10.1021/jo701628k
RECORD: Rec_0296052 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Source entry describes small-molecule/peptide conjugation at one terminus; exact terminus not explicitly assigned in source metadata
Conjugate type: carbamate; Conjugated small molecule: 9-Fluorenylmethyl chloroformate
Bio-Activity Profile
-
PaperSolid-phase-based synthesis of ureidopyrimidinone-peptide conjugates for supramolecular biomaterials. Synlett. 2015 Evidence URLhttps://doi.org/10.1055/s-0035-1560520
RECORD: Rec_0307699 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Source entry describes small-molecule/peptide conjugation at one terminus; exact terminus not explicitly assigned in source metadata
Conjugate type: amide; Conjugated small molecule: Diethyl squarate
Bio-Activity Profile
-
PaperA general route to xyloglucan-peptide conjugates for the activation of cellulose surfaces Evidence URLhttps://doi.org/10.1016/j.carres.2012.03.038
RECORD: Rec_0316971 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
mixed L/D or modified amino-acid peptide [Mixed]
None
None
Bio-Activity Profile
Antimicrobial Anticancer Hemolytic
PMID30732943 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30732943/
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