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MYP_048709
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Basic Information
Bradykinin [8-9]
Antimicrobial
Antimicrobial ▸ Antibacterial
Antiparasitic ▸ Antimalarial
Antiparasitic ▸ Antiprotozoal ▸ Antimalarial ▸ Anti-Plasmodium
Antiparasitic ▸ General antiparasitic ▸ Antiparasitic
Cardiovascular ▸ Blood pressure regulation ▸ Antihypertensive
Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory
Enzyme modulation ▸ Enzyme inhibition ▸ DPP-III Inhibitory
Enzyme modulation ▸ Enzyme inhibition ▸ DPP-IV inhibition ▸ DPP-IV inhibitory
Enzyme modulation ▸ Enzyme inhibition ▸ Protease inhibition
Metabolic ▸ Glucose metabolism ▸ Antidiabetic
Metabolic ▸ Uric acid metabolism ▸ Hypouricemic activity
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide
Other / Curated residual function label ▸ Generic enzyme inhibition annotation
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
2 amino acids
C15H23N5O3
Standard
Sequence
FR
Physicochemical Analysis
321.37 Da
9.75
0.76
0.56
0.3800
-0.85
1.49
-0.67
5.00
0.00
0.5000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
154.32
-0.61
6.0
4.0
9.0
23.0
1.0
1.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0018241 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
Bradykinin
9913
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Neuropeptide Antihypertensive Enzyme inhibitory ACE inhibitory
Angiotensin-I converting enzyme
1100 μM
IC50
RECORD: Rec_0037961 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Protease/Proteasome inhibitor
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Morpholine urea
Fluoromethyl ketone
Bio-Activity Profile
Antimicrobial Cysteine protease inhibitor Antiparasitic Antimalarial
Plasmodium vinckei
0.11 μM
IC50; Microscopy (Giemsa staining)
PMID8450035 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/8450035/
RECORD: Rec_0048301 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Carbobenzoxy
CH2F
Bio-Activity Profile
Antiparasitic Antimicrobial Antiplasmodial Cysteine protease inhibitor
PaperParaPep: a web resource for experimentally validated antiparasitic peptide sequences and their structures PMID24923818 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24923818/
RECORD: Rec_0059902 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Protease/Proteasome inhibitor
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Benzyloxycarbonyl
Fluoromethyl ketone
Bio-Activity Profile
Antimicrobial Cysteine protease inhibitor Antiparasitic Antimalarial
Plasmodium vinckei
0.033 μM
IC50; Microscopy (Giemsa staining)
PMID8450035 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/8450035/
RECORD: Rec_0062265 VERIFIED: NO
Provenance & Taxonomy
Bos taurus [Animal]
ACE-inhibitory peptide
9913
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive
PaperMOTIFS WITH POTENTIAL PHYSIOLOGICAL ACTIVITY IN FOOD PROTEINS - BIOPEP DATABASE
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