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MYP_048701
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Basic Information
DEP (Ctx-Ha peptide derivative)
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
42 amino acids
C218H342N56O51
Standard
Sequence
GWLDVAKKIGKAAFNVAKNFLLFNKAVNFAAKGIKKAVDLWG
Physicochemical Analysis
4563.39 Da
10.22
5.75
5.54
0.1370
0.26
0.67
0.18
3.60
102.38
0.1429
11000.00
11000.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1743.12
-10.24
59.0
57.0
155.0
325.0
8.0
45.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0017865 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
topology not specified [Not included yet]
noncanonical stereochemical modification [Modified]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal Hemolytic
human red blood cells
PMID22391524 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22391524/
RECORD: Rec_0074891 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
topology not specified [Not included yet]
noncanonical stereochemical modification [Modified]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Gram-negative bacterium: Escherichia coli
1.6 μM
MIC
PMID22391524 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22391524/
RECORD: Rec_0081889 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
topology not specified [Not included yet]
noncanonical stereochemical modification [Modified]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal Hemolytic
PMID22391524 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22391524/
RECORD: Rec_0108898 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
topology not specified [Not included yet]
noncanonical stereochemical modification [Modified]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
PMID22391524 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22391524/
RECORD: Rec_0214382 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
topology not specified [Not included yet]
noncanonical stereochemical modification [Modified]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Gram-positive bacterium: Staphylococcus aureus
12.9 μM
MIC
PMID22391524 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22391524/
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