MYP_048654
Basic Information
Neutrophil defensin 1 (Defensin; alpha 1) (HNP-1) (HP-1) (HP1) [Cleaved into: HP 1-56; Neutrophil defensin 2 (HNP-2) (HP-2) (HP2)]
Antimicrobial
Antimicrobial Antibiotic activity
Antimicrobial Antifungal
Toxicity / Safety Negative safety assay result Non-hemolytic
Standard
94 amino acids
C450H723N127O127S8
Standard
Sequence
MRTLAILAAILLVALQAQAEPLQARADEVAAAPEQIAADIPEVVVSLAWDESLAPKHPGSRKNMACYCRIPACIAGERRYGTCIYQGRLWAFCC
Physicochemical Analysis
10200.85 Da
6.54
-0.46
-0.83
-0.0049
0.29
0.49
0.12
49.71
102.02
0.0638
15470.00
15845.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
4018.56
-34.32
144.0
136.0
326.0
712.0
15.0
99.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0057091 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
Alpha-defensin; Defensin
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibiotic Defensin Antifungal Non-hemolytic
No Target Organism Found
RECORD: Rec_0265471 VERIFIED: NO
Provenance & Taxonomy
synthetic construct [Synthetic]
Defensin
32630
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
RECORD: Rec_0371627 VERIFIED: NO
Provenance & Taxonomy
Oryctolagus cuniculus [Animal]
Defensin
9986
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial