Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length118 amino acids

Chemical FormulaC583H931N163O160S3

DescriptionStandard

        PTALPAAHEPMLLLAVTESVANSAAFVYFTAGALRRSISGDTLPRQFPLQLRTKSLGVFAPQLQERYPDQPMELQLSARRQPLLRCRPDALHGALFGSAEAFVVLPNATRVPAFLLNI
    

Molecular Weight12879.82 Da

Isoelectric Point (pI)9.78

Net Charge (pH 7.0)3.14

Net Charge (pH 7.4) 2.95

Charge Density (pH 7.0) 0.0266

GRAVY Index0.13

Hydrophobic Moment 0.55

Boman Index0.10

Instability Index60.54

Aliphatic Index 101.02

Aromaticity 0.0763

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 2980.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 5092.47

LogP -46.64

H-bond Donors 175.0

H-bond Acceptors 168.0

Rotatable Bonds 407.0

Heavy Atoms 909.0

Ring Count 23.0

Amide Bonds 127.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0077626 VERIFIED: NO

Provenance & Taxonomy

OrganismNyctibius bracteatus [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria