Peptide Database

Peptide NameSLAY-screened peptide P1312

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length20 amino acids

Chemical FormulaC92H141N29O29S

DescriptionStandard

        SPCTLVGIAHSLHDDNPVHH
    

Molecular Weight2149.35 Da

Isoelectric Point (pI)5.95

Net Charge (pH 7.0)-2.20

Net Charge (pH 7.4) -2.62

Charge Density (pH 7.0) -0.1099

GRAVY Index-0.22

Hydrophobic Moment 0.35

Boman Index0.14

Instability Index39.45

Aliphatic Index 92.50

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 891.74

LogP -10.29

H-bond Donors 30.0

H-bond Acceptors 32.0

Rotatable Bonds 63.0

Heavy Atoms 151.0

Ring Count 6.0

Amide Bonds 20.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0377282 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

Targetrecombinant Escherichia coli surface-display screening

MethodSLAY screening

PaperAshley T Tucker, Sean P Leonard, Cory D DuBois, Gregory A Knauf, Ashley L Cunningham, Claus O Wilke, M Stephen Trent, Bryan W Davies. Discovery of Next-Generation Antimicrobials through Bacterial Self-Screening of Surface-Displayed Peptide Libraries. Cell. 2018 Jan 25;172(3):618-628.e13. doi: 10.1016/j.cell.2017.12.009. Epub 2018 Jan 4. PMID29307492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29307492/