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MYP_048597
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Basic Information
WR3 (Derived from leucocin A)
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
18 amino acids
C83H131N33O20
Standard
Sequence
WGRAFSAGVHRLARGGRG
Physicochemical Analysis
1911.14 Da
12.00
3.85
3.59
0.2137
-0.48
0.70
-0.13
1.11
54.44
0.1111
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
870.32
-10.46
34.0
25.0
61.0
136.0
4.0
17.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0346120 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Shigella flexneri 51571
67.01 μM
MIC
PaperInsights into the Antimicrobial Activity and Cytotoxicity of Engineered α-Helical Peptide Amphiphiles PMID28002968 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28002968/
RECORD: Rec_0355989 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Bacteriocin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Bacillus cereus CMCC 63301
67.01 μM
MIC
PMID28002968 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28002968/
RECORD: Rec_0357905 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Listeria monocytogenes 21662
33.5 μM
MIC
PaperInsights into the Antimicrobial Activity and Cytotoxicity of Engineered α-Helical Peptide Amphiphiles PMID28002968 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28002968/
RECORD: Rec_0361864 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Bacteriocin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Staphylococcus aureus GIM 1.160
67.01 μM
MIC
PMID28002968 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28002968/
RECORD: Rec_0384672 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Bacteriocin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Bacillus pumilus CMCC 63202
67.01 μM
MIC
PMID28002968 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28002968/
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