Peptide Database

Peptide NameRL1 (homologue of Pc-CATH1)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antifungal

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Standard StatusStandard

Sequence Length25 amino acids

Chemical FormulaC145H236N40O30

DescriptionStandard

        IKRFWPVVIRTVVAGYNLYRAIKKK
    

Molecular Weight3019.67 Da

Isoelectric Point (pI)11.17

Net Charge (pH 7.0)6.75

Net Charge (pH 7.4) 6.54

Charge Density (pH 7.0) 0.2702

GRAVY Index0.07

Hydrophobic Moment 0.77

Boman Index-0.02

Instability Index13.39

Aliphatic Index 116.80

Aromaticity 0.1600

Extinction Coeff. Reduced 8480.00

Extinction Coeff. Oxidized 8480.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1162.28

LogP -4.56

H-bond Donors 43.0

H-bond Acceptors 37.0

Rotatable Bonds 99.0

Heavy Atoms 215.0

Ring Count 6.0

Amide Bonds 25.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0323422 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyCathelicidin

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative

TargetBacillus subtilis

Activity2.344 μg/mL

MethodMIC

RECORD: Rec_0358184 VERIFIED: YES