Peptide Database

Peptide NameTransforming growth factor beta-3

Function Ontology

Immunology ▸ Immune modulation ▸ Cytokine modulation

Regulatory peptide ▸ Cell signaling / Growth factor signaling ▸ Growth factor activity

Standard StatusStandard

Sequence Length112 amino acids

Chemical FormulaC564H860N148O168S10

DescriptionStandard

        ALDTNYCFRNLEENCCVRPLYIDFRQDLGWKWVHEPKGYYANFCSGPCPYLRSADTTHSTVLGLYNTLNPEASASPCCVPQDLEPLTILYYVGRTPKVEQLSNMVVKSCKCS
    

Molecular Weight12722.40 Da

Isoelectric Point (pI)6.10

Net Charge (pH 7.0)-1.11

Net Charge (pH 7.4) -1.56

Charge Density (pH 7.0) -0.0099

GRAVY Index-0.28

Hydrophobic Moment 0.54

Boman Index0.01

Instability Index37.48

Aliphatic Index 73.93

Aromaticity 0.1161

Extinction Coeff. Reduced 22920.00

Extinction Coeff. Oxidized 23420.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 5049.34

LogP -49.22

H-bond Donors 181.0

H-bond Acceptors 179.0

Rotatable Bonds 398.0

Heavy Atoms 890.0

Ring Count 26.0

Amide Bonds 121.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0359388 VERIFIED: YES

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyTGF-beta family

Tax ID9606; 0

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide7-16; 15-78; 44-109; 48-111

Bio-Activity Profile

Function

Cytokine Growth factor TGF-beta family Growth factor signaling