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MYP_048518
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Basic Information
Antimicrobial peptide 1a (WAMP-1a; Plant defensin)
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Host defense activity
Standard
44 amino acids
C172H272N60O59S10
Standard
Sequence
AQRCGDQARGAKCPNCLCCGKYGFCGSGDAYCGAGSCQSQCRGC
Physicochemical Analysis
4445.02 Da
8.41
2.70
2.35
0.0613
-0.35
0.50
-0.09
24.64
20.23
0.0682
2980.00
3605.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1934.77
-32.07
77.0
72.0
145.0
301.0
4.0
48.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0187993 VERIFIED: YES
Provenance & Taxonomy
Triticum kiharae [Plant]; Triticum aestivum [Plant]; Aegilops tauschii [Plant]
Hevein
4565
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
multiple disulfide bonds reported, sites not specified
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Bipolaris sorokiniana
5 μg/mL
IC50
PaperPubMed PMID 19583772 PMID19583772 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19583772/
RECORD: Rec_0198482 VERIFIED: YES
Provenance & Taxonomy
Triticum kiharae [Plant]; Triticum aestivum [Plant]; Aegilops tauschii [Plant]
Hevein
4565
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
multiple disulfide bonds reported, sites not specified
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Fusarium solani
5 μg/mL
IC50
PaperPubMed PMID 19583772 PMID19583772 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19583772/
RECORD: Rec_0200711 VERIFIED: YES
Provenance & Taxonomy
Triticum kiharae [Plant]
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
4-19; 13-25; 16-44; 18-32; 37-41
Bio-Activity Profile
Antimicrobial Antifungal
Bipolaris sorokiniana
5 μg/mL
IC50
RECORD: Rec_0213733 VERIFIED: YES
Provenance & Taxonomy
Triticum kiharae [Plant]
Defensin
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Disulfide bond(s) reported
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Botrytis cinerea
20 μg/mL
IC50
PaperPubMed PMID: 19583772 | PubMed PMID: 16269343 PMID19583772;16269343 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19583772/
RECORD: Rec_0220034 VERIFIED: YES
Provenance & Taxonomy
Triticum kiharae [Plant]; Triticum aestivum [Plant]; Aegilops tauschii [Plant]
Hevein
4565
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
multiple disulfide bonds reported, sites not specified
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Fusarium verticillioides
30 μg/mL
IC50
PaperPubMed PMID 19583772 PMID19583772 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19583772/
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