Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length58 amino acids

Chemical FormulaC275H432N76O77S8

DescriptionStandard

        MGILVLVFIFISLTQHGKSRHGPDSCNHGGGLCRMGSCVSGEYVAQYCFEPIILCCKN
    

Molecular Weight6291.35 Da

Isoelectric Point (pI)7.63

Net Charge (pH 7.0)0.71

Net Charge (pH 7.4) 0.24

Charge Density (pH 7.0) 0.0122

GRAVY Index0.39

Hydrophobic Moment 0.48

Boman Index0.22

Instability Index30.46

Aliphatic Index 88.97

Aromaticity 0.0862

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3355.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2412.42

LogP -23.58

H-bond Donors 89.0

H-bond Acceptors 89.0

Rotatable Bonds 205.0

Heavy Atoms 436.0

Ring Count 10.0

Amide Bonds 61.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0197983 VERIFIED: YES

Provenance & Taxonomy

OrganismTaeniopygia guttata [other]

FamilyBeta-defensin; Defensin

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfidedisulfide bond; sites not specified

Bio-Activity Profile

Function

Antimicrobial Defensin Non-hemolytic