Peptide Database

Peptide NameProgonadoliberin-2

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Reproductive biology ▸ Reproductive modulation

Standard StatusStandard

Sequence Length62 amino acids

Chemical FormulaC321H508N92O92S2

DescriptionStandard

        QHWSHGWYPGGKREIDSYSSPEISGEIKLCEAGECSYLRPLRTNILKSILIDTLARKFQKRK
    

Molecular Weight7192.16 Da

Isoelectric Point (pI)9.34

Net Charge (pH 7.0)3.92

Net Charge (pH 7.4) 3.57

Charge Density (pH 7.0) 0.0633

GRAVY Index-0.74

Hydrophobic Moment 0.78

Boman Index-0.14

Instability Index66.56

Aliphatic Index 78.71

Aromaticity 0.0968

Extinction Coeff. Reduced 15470.00

Extinction Coeff. Oxidized 15595.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2999.74

LogP -27.96

H-bond Donors 109.0

H-bond Acceptors 100.0

Rotatable Bonds 242.0

Heavy Atoms 507.0

Ring Count 13.0

Amide Bonds 64.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0063006 VERIFIED: YES

Provenance & Taxonomy

OrganismClarias gariepinus [Animal]

FamilyProgonadoliberin

Tax ID13013

Structure & Mods

Configlinear peptide [Linear]

Chiralitynoncanonical stereochemical modification [Modified]

N-TermPyroglutamate

Other Mods10:Glycine amide

Bio-Activity Profile

Function

Hormone Endocrine Reproductive regulator

Half-LifeMammalian: 0.8 hour; Yeast: 10 min; E. coli: >10 hour