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MYP_048491
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Basic Information
Pilosulin 5
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antifungal
Standard
37 amino acids
C192H327N49O51S2
Standard
Sequence
DVKGMKKAIKGILDCVIEKGYDKLAAKLKKVIQQLWE
Physicochemical Analysis
4202.08 Da
9.47
3.75
3.51
0.1015
-0.20
0.74
-0.03
16.76
115.95
0.0541
6990.00
6990.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1653.80
-8.66
57.0
57.0
154.0
294.0
3.0
38.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0040163 VERIFIED: YES
Provenance & Taxonomy
Myrmecia banksi [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
RECORD: Rec_0125598 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-negative
PaperCAMP: Collection of sequences and structures of antimicrobial peptides PMID24265220 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24265220/
RECORD: Rec_0188266 VERIFIED: YES
Provenance & Taxonomy
Myrmecia pilosula [Animal]
Pilosulin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative Antifungal
PaperArch Biochem Biophys. 2008 Sep 15;477(2):411-6 | http://www.ncbi.nlm.nih.gov/pubmed/18544336 PMID18544336 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18544336/
RECORD: Rec_0226551 VERIFIED: NO
Provenance & Taxonomy
Jack jumper [Animal]; Insecta [Animal]
33208; 50557
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
RECORD: Rec_0235180 VERIFIED: YES
Provenance & Taxonomy
Myrmecia pilosula [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PMID18544336 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18544336/
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