Peptide Database

Peptide NameProgonadoliberin-2

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Reproductive biology ▸ Reproductive modulation

Standard StatusStandard

Sequence Length62 amino acids

Chemical FormulaC319H508N98O94S2

DescriptionStandard

        QHWSHGWYPGGKRELDSFGTSEISEEIKLCEAGECSYLRPQRRNILRNILLDALARELQKRK
    

Molecular Weight7284.18 Da

Isoelectric Point (pI)8.76

Net Charge (pH 7.0)1.93

Net Charge (pH 7.4) 1.58

Charge Density (pH 7.0) 0.0311

GRAVY Index-0.89

Hydrophobic Moment 0.71

Boman Index-0.23

Instability Index96.66

Aliphatic Index 80.32

Aromaticity 0.0806

Extinction Coeff. Reduced 13980.00

Extinction Coeff. Oxidized 14105.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3160.15

LogP -30.62

H-bond Donors 114.0

H-bond Acceptors 100.0

Rotatable Bonds 249.0

Heavy Atoms 513.0

Ring Count 11.0

Amide Bonds 66.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0282459 VERIFIED: YES

Provenance & Taxonomy

OrganismVerasper moseri [Animal]

FamilyProgonadoliberin

Tax ID98923

Structure & Mods

Configlinear peptide [Linear]

Chiralitynoncanonical stereochemical modification [Modified]

N-TermPyroglutamate

Other Mods10:Glycine amide

Bio-Activity Profile

Function

Hormone Endocrine Reproductive regulator

Half-LifeMammalian: 0.8 hour; Yeast: 10 min; E. coli: >10 hour