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MYP_048468
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Basic Information
Temporin 1OLa
Anticancer
Anticancer ▸ Antitumor
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
13 amino acids
C76H125N15O15
Standard
Sequence
FLPFLKSILGKIL
Physicochemical Analysis
1488.90 Da
10.00
1.76
1.55
0.1352
1.48
0.45
0.52
48.90
180.00
0.1538
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
476.00
1.37
16.0
17.0
49.0
106.0
3.0
12.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0181020 VERIFIED: YES
Provenance & Taxonomy
Rana okaloosae [Animal]
Temporin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anticancer Antitumor Anti-Gram-positive Anti-Gram-negative
Candida albicans ATCC 10231
12.5 μM
MIC
PMID17005262;29842923 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17005262/
RECORD: Rec_0217825 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Anticancer
RECORD: Rec_0259297 VERIFIED: YES
Provenance & Taxonomy
Rana okaloosae [Animal]
Temporin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anticancer Antitumor Anti-Gram-positive Anti-Gram-negative
Klebsiella pneumoniae ATCC 13883
50 μM
MIC
PMID17005262;29842923 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17005262/
RECORD: Rec_0272958 VERIFIED: YES
Provenance & Taxonomy
Rana okaloosae [Animal]
Temporin
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PaperPubMed PMID: 17005262 PMID17005262 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17005262/
RECORD: Rec_0276060 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Temporin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
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