Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length99 amino acids

Chemical FormulaC516H832N144O145S9

DescriptionStandard

        MELFLIITILLFQKPTVTEQLKKCWDNHIQGRCRRICKITERHEALCGNERYCCLSIKDMEARKRITQPPHPKPPTFALTLPQDNDIIDTSPSQKVYYM
    

Molecular Weight11661.59 Da

Isoelectric Point (pI)8.81

Net Charge (pH 7.0)3.71

Net Charge (pH 7.4) 3.23

Charge Density (pH 7.0) 0.0375

GRAVY Index-0.47

Hydrophobic Moment 0.77

Boman Index-0.10

Instability Index53.65

Aliphatic Index 83.74

Aromaticity 0.0707

Extinction Coeff. Reduced 9970.00

Extinction Coeff. Oxidized 10345.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4669.42

LogP -39.82

H-bond Donors 165.0

H-bond Acceptors 161.0

Rotatable Bonds 387.0

Heavy Atoms 814.0

Ring Count 19.0

Amide Bonds 107.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0024352 VERIFIED: NO

Provenance & Taxonomy

OrganismPropithecus coquereli [Bacterium]

FamilyDefensin

Tax ID379532

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic

MethodQualitative functional evidence