Peptide Database

Peptide NameDefensin 1

Function Ontology

Antimicrobial

Antimicrobial ▸ Antifungal

Antimicrobial ▸ Antifungal ▸ Fungicidal activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length73 amino acids

Chemical FormulaC352H551N95O108S10

DescriptionStandard

        MEKKSVGVLSFLFLVLFVTQEMVVTEAKTCEHLADTYRGPCFTDASCDDHCKNKAHLISGTCHNLQCFCTQNC
    

Molecular Weight8162.36 Da

Isoelectric Point (pI)6.00

Net Charge (pH 7.0)-2.22

Net Charge (pH 7.4) -2.77

Charge Density (pH 7.0) -0.0304

GRAVY Index0.05

Hydrophobic Moment 0.55

Boman Index0.07

Instability Index24.05

Aliphatic Index 72.05

Aromaticity 0.0822

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1990.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3256.15

LogP -34.62

H-bond Donors 119.0

H-bond Acceptors 120.0

Rotatable Bonds 270.0

Heavy Atoms 565.0

Ring Count 11.0

Amide Bonds 78.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0179764 VERIFIED: NO

Provenance & Taxonomy

OrganismLens culinaris [Bacterium]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antifungal Fungicidal Non-hemolytic Non-ribosomal