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MYP_048357
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Basic Information
Gaegurin-5 (1-13)[V8A,A9L,V12L], PTP7
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Anti-biofilm ▸ Biofilm inhibition
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
13 amino acids
C71H117N15O15
Standard
Sequence
FLGALFKALSKLL
Physicochemical Analysis
1420.78 Da
10.00
1.76
1.55
0.1352
1.48
0.55
0.48
-15.39
165.38
0.1538
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
484.79
-0.15
17.0
17.0
48.0
101.0
2.0
12.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0395532 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Gaegurin-derived
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Anticancer
MCF-7, MCF-7/DOX
PaperIn vitro activities of native and designed peptide antibiotics against drug sensitive and resistant tumor cell lines PMID14499271 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/14499271/
RECORD: Rec_0414589 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Gaegurin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Staphylococcus aureus ATCC 25923
4 μM
MIC
PMID15894405;14499271;19464332;21887652;22526264 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15894405/
RECORD: Rec_0420042 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Gaegurin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Staphylococcus aureus ATCC 29213
8 μM
MBC
PMID15894405;14499271;19464332;21887652;22526264 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15894405/
RECORD: Rec_0422926 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Gaegurin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Staphylococcus aureus ATCC 43300
8 μM
MBC
PMID15894405;14499271;19464332;21887652;22526264 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15894405/
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