Peptide Database

Peptide NameSyn-safencin-51

Function Ontology

Antiparasitic ▸ General antiparasitic ▸ Antiparasitic

Venom / Toxin ▸ General toxin ▸ Toxicity

Standard StatusStandard

Sequence Length25 amino acids

Chemical FormulaC143H238N42O32

DescriptionStandard

        AGKETIRQYLKNKIKKKWRKAVIAW
    

Molecular Weight3057.68 Da

Isoelectric Point (pI)10.79

Net Charge (pH 7.0)7.79

Net Charge (pH 7.4) 7.59

Charge Density (pH 7.0) 0.3116

GRAVY Index-0.96

Hydrophobic Moment 0.71

Boman Index-0.30

Instability Index10.18

Aliphatic Index 86.00

Aromaticity 0.1200

Extinction Coeff. Reduced 12490.00

Extinction Coeff. Oxidized 12490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1263.18

LogP -7.22

H-bond Donors 46.0

H-bond Acceptors 40.0

Rotatable Bonds 109.0

Heavy Atoms 217.0

Ring Count 5.0

Amide Bonds 26.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0055568 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyBacteriocin

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antiparasitic

TargetL. donovani

Activity6.36 μM

MethodIC50

RECORD: Rec_0271250 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyBacteriocin

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antiparasitic Toxicity

TargetTHP-1 cells

Activity<20 μM

MethodCC50