Peptide Database

Peptide NameDefb14-1CV(6-17)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Standard StatusStandard

Sequence Length12 amino acids

Chemical FormulaC67H113N25O13

DescriptionStandard

        LRKFFARIRGGR
    

Molecular Weight1476.77 Da

Isoelectric Point (pI)12.00

Net Charge (pH 7.0)4.76

Net Charge (pH 7.4) 4.55

Charge Density (pH 7.0) 0.3966

GRAVY Index-0.58

Hydrophobic Moment 0.59

Boman Index-0.43

Instability Index28.43

Aliphatic Index 73.33

Aromaticity 0.1667

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 657.04

LogP -5.23

H-bond Donors 26.0

H-bond Acceptors 18.0

Rotatable Bonds 51.0

Heavy Atoms 105.0

Ring Count 2.0

Amide Bonds 11.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0371646 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyDefensin

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative

TargetMonomer: [Pseudomonas aeruginosa PAO1

Activity2 μM

MethodMIC

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