Peptide Database

Peptide NameSLAY-screened peptide P329

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length20 amino acids

Chemical FormulaC109H171N27O32S

DescriptionStandard

        LPETEALPYRCNIWITLNKE
    

Molecular Weight2403.75 Da

Isoelectric Point (pI)5.01

Net Charge (pH 7.0)-1.24

Net Charge (pH 7.4) -1.47

Charge Density (pH 7.0) -0.0619

GRAVY Index-0.40

Hydrophobic Moment 0.27

Boman Index0.01

Instability Index72.44

Aliphatic Index 102.50

Aromaticity 0.1000

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 6990.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 961.12

LogP -6.03

H-bond Donors 33.0

H-bond Acceptors 32.0

Rotatable Bonds 75.0

Heavy Atoms 169.0

Ring Count 5.0

Amide Bonds 21.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0240306 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

Targetrecombinant Escherichia coli surface-display screening

MethodSLAY screening

PaperAshley T Tucker, Sean P Leonard, Cory D DuBois, Gregory A Knauf, Ashley L Cunningham, Claus O Wilke, M Stephen Trent, Bryan W Davies. Discovery of Next-Generation Antimicrobials through Bacterial Self-Screening of Surface-Displayed Peptide Libraries. Cell. 2018 Jan 25;172(3):618-628.e13. Epub 2018 Jan 4. PMID29307492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29307492/