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MYP_048168
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Basic Information
Brevinin-1DYa
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
20 amino acids
C109H177N23O22S2
Standard
Sequence
FLSLALAALPKFLCLVFKKC
Physicochemical Analysis
2225.84 Da
9.39
2.74
2.50
0.1369
1.58
0.53
0.44
21.25
146.50
0.1500
0.00
125.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
705.72
0.07
26.0
27.0
72.0
156.0
4.0
19.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0304100 VERIFIED: YES
Provenance & Taxonomy
Rana amurensis [Animal]
Brevinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Escherichia coli
512 μM
MIC
PMID29366784 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29366784/
RECORD: Rec_0322449 VERIFIED: YES
Provenance & Taxonomy
Rana amurensis [Animal]
Brevinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
Horse RBC
17 μM
HC50
PMID29366784 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29366784/
RECORD: Rec_0326544 VERIFIED: YES
Provenance & Taxonomy
Rana huanrensis [Animal]
Brevinin
Structure & Mods
Linear peptide with a single intramolecular disulfide-stabilized loop [Linear]
Gene-encoded natural peptide composed of standard L-amino acids [L]
14-20
Bio-Activity Profile
Antimicrobial Antibacterial
Evidence URLhttps://www.uniprot.org/uniprotkb/Q06B79/entry
RECORD: Rec_0332178 VERIFIED: NO
Provenance & Taxonomy
Amphibia [Animal]
Brevinin
8292
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
14-20
Bio-Activity Profile
Antimicrobial
RECORD: Rec_0332568 VERIFIED: YES
Provenance & Taxonomy
Rana dybowskii [Animal]
Brevinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Escherichia coli
15 μM
MIC
PMID17688900 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17688900/
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