Peptide Database

Peptide NameLysozyme

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Bacteriolytic activity ▸ Bacteriolytic enzyme

Enzyme / Catalytic activity ▸ Hydrolase

Enzyme / Catalytic activity ▸ Hydrolase ▸ Glycosidase

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length166 amino acids

Chemical FormulaC846H1325N225O235S8

DescriptionStandard

        MPKLPAPLRKKLIALVLAGAGTFTIATHYTGYWEGKENSTYIDPTGTPTICYGHTGPDVKPGMTLTDEECLELLEKDMKWAFAAIDRRVQVPLTRGQTVALASWIFWAGETNFRNSTLLRLINAGQMPASCKQYIRWIYSKGVKLPGLEARRTADEWLCRYDLPKV
    

Molecular Weight18664.46 Da

Isoelectric Point (pI)9.06

Net Charge (pH 7.0)4.65

Net Charge (pH 7.4) 4.23

Charge Density (pH 7.0) 0.0280

GRAVY Index-0.22

Hydrophobic Moment 0.57

Boman Index0.04

Instability Index33.49

Aliphatic Index 84.70

Aromaticity 0.1024

Extinction Coeff. Reduced 43430.00

Extinction Coeff. Oxidized 43680.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7333.41

LogP -64.49

H-bond Donors 261.0

H-bond Acceptors 250.0

Rotatable Bonds 601.0

Heavy Atoms 1314.0

Ring Count 36.0

Amide Bonds 173.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0203169 VERIFIED: NO

Provenance & Taxonomy

OrganismEscherichia coli O111:H11 str. CVM9455 [Bacterium]

FamilyGlycosyl hydrolase 24

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Bacteriolytic enzyme Glycosidase Hydrolase Non-hemolytic Non-ribosomal

MethodQualitative functional evidence